Journal
Mechanism ReviewNo. 04

What 660nm actually does.

A short, annotated reading of the published research on red light and skin tissue. Mechanism first. Claims last, if at all.

( 01 )

Absorption

Light at 660 nanometres penetrates the upper layers of skin, where it is absorbed by cytochrome c oxidase, an enzyme in the mitochondrial respiratory chain. 1

( 02 )

Energy

Absorption is associated in published studies with increased ATP production, the energy currency cells use for maintenance and renewal. 2

( 03 )

Signal

Researchers describe this as photobiomodulation. Light as a signal to tissue, not a treatment applied onto it. 3

Restoration Belt, edge glow and side control unit

Fig. 1 · Restoration Belt

The array faces inward. In use, only the edge glow and the side control unit are visible. 630 to 660nm, calibrated to a twelve-minute session.

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From the literature
A biphasic dose response has been frequently observed where low levels of light have a much better effect on stimulating and repairing tissues than higher levels of light.

Huang, Chen, Carroll & Hamblin, Dose-Response 7(4), 2009

Mechanistic review of the light-dose literature

What it does not show — A review, not a trial. It does not tell you the optimal dose for any one device or any one face — only that 'more' stops helping and then starts hurting.

Verify on PubMed · PMID 20011653

References

1. Hamblin, M. Mechanisms of low level light therapy. 2017.
2. de Freitas & Hamblin. Proposed mechanisms of photobiomodulation. 2016.
3. Anders et al. Low-level light/laser therapy versus photobiomodulation therapy. 2015.

Mechanism, at home.

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The Sunday Protocol

The research we read this week, summarised without hype.

Zential Pure( 04 / 05 )